PULSATILE MULTI-SCALE FLUID STRUCTURE INTERACTION MODELING FOR OPTIMAL LEFT VENTRICULAR ASSIST DEVICE IMPLANTATION
A Left Ventricular Assist Device (LVAD), is a mechanical pump designed to supplement circulatory requirements and reduce the workload of a failing heart, allowing for partial recovery of myocardial functionality as well as a destination therapy. Despite improvements in device design and anticoagulation treatment, VADs have a 20% to 40% chance of causing a thrombo-embolism event after 6 months. Stroke incidence can be significantly reduced by adjusting the VAD outflow cannula to direct particles away from the cerebral vessels. In this study, we build upon our previous work that generated a time-dependent multi-scale CFD analysis of patient-specific geometry models of the VAD-bed vasculature and combine it with a Finite Element Analysis (FEA) to account for vessel compliance, generating a Fluid Structure Interaction (FSI) to further explore this hypothesis.